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KMID : 1145920190240020037
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Journal of Mycology and Infection
2019 Volume.24 No. 2 p.37 ~ p.44
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Fungal Genomics in Dermatology
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Lee Young-Bok
Lee Soo-Young
Seo Ji-Min
Kang Min-Ji
Yu Dong-Soo
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Abstract
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To date, hundreds of fungal genomes have been sequenced, and many more are underway. Recently developed cutting-edge techniques generate very large amounts of data, and the field of fungal genomics in dermatology has consequently evolved substantially. Methodological improvements have broadened the scope of large-scale ecological studies in dermatology, including biodiversity assessments and genomic identification of fungi. Here, we aimed to provide a brief introduction to bioinformatic approaches to fungal genomics in the field of dermatology. We described the history and basic concepts of fungal genomics and presented sequencing-based techniques for fungal identification, including a list of the revised taxa of dermatophytes, as determined by current phylogenetic analysis. Finally, we discussed the emerging trends in fungal genomics in dermatology, such as next-generation sequencing.
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KEYWORD
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Fungal genomics, Next-generation sequencing
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